Projects

Project Description

Multiple Myeloma is a plasma cell disorder accounting for approximately 12% of all hematological malignancies characterized by clonal proliferation of terminally differentiated B lymphoid cells, which accumulate in bone marrow and produce a monoclonal protein (Immunoglobulin), usually IgG or IgA, often referred to as M or myeloma protein. The incidence of multiple myeloma (MM) is known to be variable according to ethnicity and is increasing rapidly in Asian countries. Although vast data is available in literature, Indian data is not readily available to assess disease burden and its management issues. The age of MM onset can be determined so that early identification and intervention can be instituted since there are reports that patients present themselves to OPD in fifth decade of life which has been attributed to westernized diet and exposure to pollutants. Our institution is a referral center for surrounding rural population and this could help in evaluating both urban and rural (referred) patients. It will help in evaluating whether protein electrophoretic patterns reported in various parts of the country is like our population under study. This study - an attempt to understand the clinical, biochemical and haematological patterns amongst patients who have been diagnosed of monoclonal gammopathy in our hospital population.