Publications
Traditional versus reverse algorithm for diagnosis of syphilis – An Indian perspective from a national referral laboratory for sexually transmitted infections
Verma S, Panda PS, Muralidhar S, Rajan S, Khunger N. Syphilis diagnosis can be confirmed by two testing algorithms. In the traditional algorithm, a nontreponemal test is used as a screening test to rule out syphilis which, if reactive, is confirmed by a treponemal test. In the reverse algorithm, a treponemal test is used as a screening test, which, if positive, is confirmed by a nontreponemal test. If the nontreponemal is negative, a second treponemal assay of a different principle is performed to resolve the discordant result. The aim of this study was to compare the traditional and reverse algorithms for the diagnosis of syphilis in a National Referral Apex Centre for Sexually Transmitted Infections.
