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Palmar granuloma annulare is a rare subtype of granuloma annulare (GA). It can occur along with lesions of granuloma annulare elsewhere or in isolation. However, isolated lesions occurring over the palms possess a diagnostic dilemma because many other cases share similar clinical features.

Therefore, histology is essential to arrive at a correct diagnosis.

Often, palmar GA lesions may lack the characteristic histologic features of palisading granulomas but have an interstitial pattern of inflammation.

Hence it is imperative to be aware with all the morphologic variants of GA in order to make a reliable diagnosis.