Publications

Hodgkin’s disease is usually a disease involving the peripheral lymphatic system with strong predilection to the cervical lymph nodes. Diagnosis is made by a combination of histopathology (where the Reed-Sternberg giant cell is pathognomonic) as well as by lymphocytic markers such as CD20 and CD30. Hodgkin’s disease rarely involved the brain and non-lymphoid organs. We present a known case of Hodgkin’s disease with a lesion in the frontal lobe which presented as new onset seizures in a 29-year-old patient. The lesion was successfully removed and on analysis was seen to be a part of Hodgkin’s disease. The rarity of CNS involvement coupled with a recurrent pattern of this disease (the CNS involvement seen in the recurrence rather than the primary presentation) makes this a rare and interesting report.

Keywords: Hodgkin’s Disease; Brain; Immunocompetent; Deadly Occurrence