Middle lobe syndrome- a rare but an important clinical entity
ABSTRACT
Middle lobe syndrome refers to a clinical condition that is characterized by recurrent or chronic collapse of the middle
lobe of the right lung. Inefficient collateral ventilation, infection and inflammation in the middle lobe or lingula are
thought to play a role in the pathogenesis of this condition. MLS can be obstructive or non-obstructive; the
management varies according to the aetiology. Patients with proven endobronchial lesions or malignancy are usually
offered surgical resection while most patients with non-obstructive aetiology respond to medical treatment consisting
of bronchodilators, mucolytics and broad-spectrum antibiotics. We present a case of MLS who was managed
conservatively in our ICU but did not respond and required surgical intervention later.