Factors affecting achievement of glycemic targets among type 2 diabetes patients in South Asia: Analysis of the CARRS trial
Abstract
Objective:
To assess the predictors of achieving and maintaining guideline-recommended glycemic control in people with poorly controlled type 2 diabetes.
Methods:
We analyzed data from the Centre for Cardiometabolic Risk Reduction in South Asia (CARRS) Trial (n=1146), to identify groups that achieved guideline-recommended glycemic control (HbA1c<7%) and those that remained persistently poorly controlled (HbA1c>9%) over a median of 28 months of follow-up. We used generalized estimation equations (GEE) analysis for each outcome i.e. achieving guideline-recommended control and persistently poorly controlled and constructed four regression models (demographics, disease-related, self-care, and other risk factors) separately to identify predictors of HbA1c<7% and HbA1c>9% at the end of the trial, adjusting for trial group assignment and site.