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Publications

Factors affecting achievement of glycemic targets among type 2 diabetes patients in South Asia: Analysis of the CARRS trial

Groups and Associations Muhammad Q Masood 1,*, Kavita Singh 2,*, Dimple Kondal 3, Mohammed K Ali 4, Minaz Mawani 5, Raji Devarajan 6, Usha Menon 7, Premlata Varthakavi 8, Vijay Viswanathan 9, Mala Dharmalingam 10, Ganapathi Bantwal 11, Rakesh Sahay 12, Rajesh Khadgawat 13, Ankush Desai 14, Dorairaj Prabhakaran 15, K M Venkat Narayan 16, Nikhil Tandon
Diabetes Res Clin Pract 2022

Abstract

Objective:

To assess the predictors of achieving and maintaining guideline-recommended glycemic control in people with poorly controlled type 2 diabetes.

Methods:

We analyzed data from the Centre for Cardiometabolic Risk Reduction in South Asia (CARRS) Trial (n=1146), to identify groups that achieved guideline-recommended glycemic control (HbA1c<7%) and those that remained persistently poorly controlled (HbA1c>9%) over a median of 28 months of follow-up. We used generalized estimation equations (GEE) analysis for each outcome i.e. achieving guideline-recommended control and persistently poorly controlled and constructed four regression models (demographics, disease-related, self-care, and other risk factors) separately to identify predictors of HbA1c<7% and HbA1c>9% at the end of the trial, adjusting for trial group assignment and site.