ComparisonofVolumeControlledVentilationwithPressureControlled VentilationDuringLumbarSpineSurgeryinPronePosition:ARandomized ControlledStudy
ackground:Different modesof mechanicalventilationsuchasvolumecontrolled ventilation(VCV)and
Pressure Controlled Ventilation (PCV) are deployed to balance respiratory mechanics, gas exchange and
hemodynamicsinpatientsundergoinglumbarspinesurgeriesinproneposition.Methods:Thisprospective
studyincluded72patientsundergoinglumbarspinesurgeriesinproneposition.Theywererandomizedto
twoGroups–GroupV(whoreceivedvolumecontrolledventilation)andGroupP(whoreceivedpressure
controlled ventilation). The ventilation and hemodynamic parameters were statistically analyzed at 5 min
afterintubationinsupine(S5),60minafterprone(P60)and180minafterprone(P180)position.Oxygenation
parameterswereassessedfromABGinsupine(baseline)andattheendofsurgeryinproneposition.Chi-
square, independent t-test and ANOVA were used to compare the data between the two groups. Results:
Demographics, oxygenation and hemodynamics were comparable between the two groups. P peak and P
meanincreasedfromsupinetopronepositioninboththegroups.ThePpeakinVCVwashigherthanPCV
inpronepositionandthedifferencewassignificantatfirsthour[p=0.008].Thedynamiccompliance(Cdyn)
decreasedinbothPCVandVCVfromsupinetoproneposition.There wassignificant increasein Cdyn in
PCVattheendoffirsthourinproneposition(p=0.005).Vte,MV,PEEP,RR,EtCO2,
andVD
/VT
didnotshow
anysignificantdifferencebetweenthegroups(p>0.05).Conclusion:BothVCVandPCVcanbesafelyusedto
ventilatepatientsinpronepositionundergoinglumbarspinesurgeries.