Publications
An ominous ‘Halo’—extensive pulmonary metastases from a hepatic angiosarcoma
Sreedhar Jayakrishnan Cherulil, Sreelesh Kombath Payini, Ramakrishnan Kg A 64-year-old male patient presented with a 2-week history of right-sided abdominal discomfort and significant weight loss. Per abdomen examination showed hepatomegaly. Computed tomography (CT) of the abdomen showed chronic liver disease with a large irregular hypo attenuating lesion with heterogenous and peripheral rim enhancement and multiple smaller lesions, suggestive of hepatic angiosarcoma. CT thorax showed multiple enhancing solid nodules with surrounding peripheral ground glass opacities, the ‘Halo Sign’which is distinctive for pulmonary metastases from a primary angiosarcoma (Figure 1). Biopsy from the liver lesion showed a poorly differentiated neoplasm positive for
CD 31 (Cluster of Differentiation) and ERG (Erythroblast transformation specific related gene) on immunohistochemical staining, confirming a diagnosis of hepatic angiosarcoma. The patient had a deterioration of his clinical …
