Publications
A real world multi center study on efficacy and safety of natalizumab in Indian patients with multiple sclerosis
Mathew T, Kamath V, John SK, Netravathi M, Iyer RB, Raghavendra S, Kumar S, Neeharika ML, Gupta S, Murgod U, Shivakumar R, Annadure RK, Ichaporia N, Rohatgi A, Nair SS, Yareeda S, Anand B, Singh P, Renukaradhya U, Arulselvan V, Reddy YM, Surya N, Sarma GRK, Nadig R, Deepalam S, Sharath Kumar GG, Satishchandra P, Singhal BS, Parry G Background: Natalizumab (NTZ) is increasingly being used in Indian multiple sclerosis (MS) patients. There are no reports on its safety and efficacy, especially with respect to the occurrence of progressive multifocal leukoencephalopathy (PML).
Objectives: To describe the patient characteristics, treatment outcomes, and adverse events, especially the occurrence of PML in NTZ-treated patients.
Methods: A multicentre ambispective study was conducted across 18 centres, from Jan 2012 to Dec 2021. Patients at and above the age of 18 years treated with NTZ were included. Descriptive and comparative statistics were applied to analyze data.
