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Research Institute

List of projects with S.I. No, Project Title, Project Lead, Project Type, Year of Initiation, and Status.
S.I. No Project Title Project Lead Project Type Year of Initiation Status
1 From Dysplasia to Carcinoma: Profiling the Inflammatory and Fibrogenic Influences on Epithelial Plasticity in Oral Cancer to disinter the early transition genes Dr. Madhumathy G Nair DBT 2026 Ongoing
2 Overcoming the Anabolic Block in patients with TB with a focus on Cachexia through anti-inflammatory strategies in South India: A Randomised controlled trial Biotechnology Industry Association Research Assistance Council (BIRAC), India 2025 Ongoing
3 Development of an immunohistochemistry-based assay predicting lymphatic spread in oral cancer Dr. Madhumathy G Nair, Dr. Gayatri R RGUHS 2025 Ongoing
4 SecureUS: Development and Field Validation of the Advanced Secure Ultrasound Imaging System in Primary Healthcare Settings. Dr Tony Raj ICMR Intermediate grant 2025 Ongoing
5 ICMR -Centre for advanced research in maternal and child nutrition using artificial intelligence and stable isotope techniques (MANASI) Dr Pratibha Dwarkanath, Prof. Anura V Kurpad, Dr. Tinku Thomas, Dr Shalini Hegde, Dr Ambily Sivadas 2025 Ongoing
6 Metabolic engineering of human gut microbiome for improved micronutrient status – a Proof of concept using stable isotopic probes ICMR 2025 Ongoing
7 ADAM: Advancing Diabetes Management-Integration of continuous glucose monitoring with artificial intelligence for personalized diet interventions in diabetes by ICMR ICMR 2025 Ongoing
8 Autoimmune Rheumatologic Disease Education Drive (RheumED) Dr. Vineeta Shobha 2024 Ongoing
9 Improving glycemic control in urban primary care settings Dr. Farah Fathima 2024 Ongoing
10 Implementation of a Technology-driven AMSP program Steered by Clinicians to Improve Antimicrobial Prescribing: a multi-centric mixed-methods study Dr. Savitha Nagaraj ICMR Intermediate grant 2024 Ongoing
11 Immediate Kangaroo Mother Care (i-KMC) study Dr. Suman Rao 2024 Ongoing
12 Indian Child Growth Reference Development Research Initiative – ICMR (South Zone) Indian Council of Medical Research (ICMR), New Delhi 2024 Ongoing
13 Implementation Research to develop an optimized model of comprehensive intervention package and delivery strategies to reduce stillbirths at sub-district level in Karnataka. Dr. Prem K. Mony 2024 Ongoing
14 ICMR Initiative Consortium on Stillbirth Study (Secondary Analysis) ICMR 2024 Completed
15 PORTENT - Evaluation and Validation of Truenat® Malaria Pv-Pf (a new Q-PCR device for malaria testing by MolBio) over a 1-year period. Dr Mary Dias NIH–NIBIB POCTRN 2024 Ongoing
16 Plasma metabolomic and genomic correlates of dysregulated innate immune system in South Asian Indians Type 2 Diabetics Department of Biotechnology, India 2024 Ongoing
17 Single-digit Neonatal Mortality Rate (NMR) study [Sankalp] Dr. Prem K. Mony 2024 Ongoing
18 Development and evaluation of effectiveness of improved take home foods in combination with behaviour change intervention to improve nutritional status in children in selected districts of six states of India: A Cluster Randomized Controlled Trial (The NECCTAR trial) Indian Council of Medical Research 2024 Ongoing
19 Impact of Different Doses of Vitamin D Supplementation During Pregnancy on Preterm Births in South India: A Double-Blind Randomized Controlled Trial PhD Scholar: Gowri Bhatnagar; Supervisor: Dr. Pratibha Dwarkanath Co-supervisor: Dr Mary Dias; Division of Nutrition, St. John’s Research Institute 2023 Ongoing
20 Investigating the paradox of intra-individual double burden of anthropometric undernutrition and metabolic overnutrition in Indian Children: a prevention paradigm Department of Biotechnology 2023 Ongoing
21 Pediatric Epidemiology and Child Health - Prospective Cohort Study in India 2023 Ongoing
22 Development of an AI based inage assisted ChatBot for dietary recall and nutrient intake calculation. Dr Tinku Thomas 2023 Ongoing
23 POCTRN – Point of Care Technologies for Nutrition, Infection and Cancer for Global Health (PORTENT) Study: Evaluation and selection of a total of five (05) Point-of-Care Devices for Nutrition, Infection, and Cancer for Global Health for validation over a 5-year period. Dr Tony Raj NIH–NIBIB POCTRN 2023 Ongoing
24 Secondary Analysis: PRAYAS – Protocol for Pooled Research and Analysis for Yielding Anemia-free Solutions in India ICMR 2023 Ongoing
25 SUPPORT -Strategies for non-communicable disease prevention in select populations in different regions of India PI- Dr Denis Xavier Co-I- Dr. Deepa Srinivasan, Dr. Aakanksha Singh, Dr. Ryan Fernandez, Ms. Freeda DCRT 2023 Completed
26 Bayesian Heirarchical modeling techiniques for the evaluation of nutrition specific program in India using data from national surveys: Creating a frame work for prospective evaluation Dr Tinku Thomas 2023 Ongoing
27 Carbohydrate intake and its effects on insulin, body weight and components of energy expenditure Indian Council of Medical Research 2023 Completed
28 Estimation of protein requirement and body composition in healthy Indian children aged 1-5 years Indian Council of Medical Research 2023 Completed
29 Optimization of Supplementary Nutrition Provisions of the Integrated child Development Service of India 2022 Completed
30 Low-Dose Calcium Trial: Secondary Analyses to Inform Pre-Eclampsia Definitions Harvard T.H. Chan School of Public Health / Bill & Melinda Gates Foundation 2022 Completed
31 Oral Vitamin D Supplementation as a Safe, Affordable Treatment for Profound Vitamin D Deficiency in Pregnancy (UPLIFT) Medical Research Council (MRC), UK 2022 Completed
32 Impact of Vitamin D Supplementation on Preterm Births and Pre-Rupture of Membranes: A Double-Blind Randomized Controlled Trial Department of Biotechnology (DBT), Govt. of India 2022 Ongoing
33 Pregnancy outcomes and it’s determinants at a tribal hospital in south India– A prospective cohort study (PREDICT) PI- Dr. Denis Xavier, Co-I : Dr. Padmini Devi , Dr Deepa. S, Dr. Ryan Fernandez DCRT 2022 Completed
34 Evaluation of the effectiveness of a specially designed food product in promoting weight gain and changes in body composition in children with Severe Acute Malnutrition Dr Sumathi Swaminathan and thereafter Dr Nancy Angeline Karnataka Innovation and Technology Society 2022 Ongoing
35 Strategic understanding of mechnaisms that restrict grain yield, grain protein content and quality in rice through an interface between clinical nutrition and agriculture research DBT 2021 Ongoing
36 Powdered egg: Improving egg consumption in India Dr Sumathi Swaminathan Sight and Life and N4D 2021 Completed
37 Oral Vitamin D Supplementation as a Safe, Affordable Treatment for Profound Vitamin D Deficiency in Pregnancy (Seed Funding) Medical Research Council (MRC), UK 2021 Completed
38 Evaluation and Optimization of the NCD Screening and Management Tool - A Three Arm Quasi- Experimental Study in selcted Talukas of Karnataka Dr. Tony D.S. Raj Foreign 2021 Completed
39 The efficacy of amino acid supplementation in treating environmental enteric dysfunction among children at risk of malnutrition International Atomic Energy Agency 2021 Ongoing
40 Measurement of energy expenditure and energy requirement of active elderly from urban South India Department of Biotechnology 2021 Completed
41 Fuel Supply to the Human Placenta: Maternal Obesity and Placental Trafficking of Amino Acids and Fatty Acids Department of Biotechnology, India 2021 Completed
42 An Integrative Omics approach to Enabling Precision Medicine for Anti- Diabetic therapy in Indian population DBT/Wellcome Trust India Alliance 2021 Ongoing
43 Contractual Project for conducting pre-clinical studies to characterize the molecular mechanism of chemo sensitization of selected cancer cell lines by a novel compound. Dr. Madhumathy G Nair Industry sponsored 2021 Completed
44 MITHRA: Mobile Mental Health in Community-Based Organizations: A Stepped Care Approach to Women's Mental Health Dr Krishnamachari Srinivasan and Dr Amritha Bhat NIH 2021 Completed
45 Impact of Probiotic Consumption on Depression in Peri-Menopausal Women (41–48 years) in Urban Delhi 2021 Completed
46 Periconceptional Surveillance for Prevention of Anemia and Birth Defects in India 2021 Ongoing
47 Clinical Research Training Programme Wellcome Trust DBT India Alliance 2020 Completed
48 ACT Study - Anti-Coronavirus Therapies (ACT) to prevent progression of COVID-19: Randomized trials PI: Dr. Denis Xavier, Co-I: Dr. Prem Pais / Dr.Atiya Faruqui/ Dr. Bhuvana K B Population Health Research Institute (PHRI) 2020 Completed
49 Optimizing nuclear techniques to assess accurate quantitative biomarkers of added sugar intake in adults International Atomic Energy Agency 2020 Completed
50 PK-HCQ Study PI: Dr. Denis Xavier; Dr. Bhuvana KB Norwich Clinical Services Pvt. Ltd. 2020 Completed
51 Urinary metabolomics for monitoring Lysine sufficiency in malnourished infants receiving lysine fortified food Indo French Centre for the Promotion of Advanced Research 2020 Completed
52 Role of protein and vitamin B12 in clinical and public health nutrition in India 2020 Completed
53 Human placental amino acid sensing and transport in Indian women: Role in Fetal Growth Restriction Rajiv Gandhi University of Health Sciences, India 2020 Completed
54 De novo lipogenesis in adiposity and glycaemic control: Epigenetic mechanisms and associated metabolite profiles DBT/Wellcome Trust India Alliance 2020 Ongoing
55 Accurate estimation of changes in body composition, energy balance and nutritional status of Indian children with acute lymphoblastic leukaemia (ALL) during cancer treatment International Atomic Energy Agency 2019 Ongoing
56 Distributed Intelligent Ultrasound Imaging System for Secure in-community Diagnostics (SecureUltrasound) PI: Prof. Rajkumar Roy (Cranfield University, UK), Co-I: Dr. Tony Raj EPSRC Global Challenges Research Fund 2019 Completed
57 Evaluating role of circulating DNA as biomarkers of tumor progression and response to therapy in neo-adjuvant setting of breast cancer - a pilot study Dr. Madhumathy G Nair, Dr. Rakesh S Ramesh, Dr. Jyothi S Prabhu RGUHS 2019 Completed
58 To investigate the role of miR-18a in regulating metastatic progression of breast cancer. Dr. Madhumathy G Nair ICMR-DHR 2019 Completed
59 Estimating lysine bioavailability of Indian vegetarian meal using indicator amino acid oxidation method in adults Indian Council of Medical Research 2019 Completed
60 Estimation of total energy expenditure and physical activity level among young adults Indian Council of Medical Research 2019 Completed
61 Community Health Workers Perceptions of a chronic Disease and Mental Health Care Intervention in Karnataka. Dr. Tony D.S. Raj University of California 2019 Completed
62 Stable isotope studies to understand Vitamin D dose response on Bone Reabsorption rates and fractional Calcium absorption in vitamin D Defficient and sufficient stage Dr. Tony D.S. Raj DBT 2019 Completed
63 Indo Finland joint call for Mobility of Researchers Dr. Tony D.S. Raj Government 2019 Completed
64 ACHIEVE -Aldosterone bloCkade for Health Improvement EValuation in End-stage renal disease Dr Denis Xavier CIHR (Canadian Institutes of Health Research) through Population Health Research Institute (PHRI), McMaster University, Canada. 2019 Completed
65 Does BRCA1 deficiency dictate the chemosensitivity in serous ovarian tumors? Evaluation of BRCA1 dysfunction by multimodality testing Dr Jyothi S Prabhu "Kidwai Memorial Institute of Oncology " 2019 Completed
66 An Interventional, Randomized, Parallel Group, Placebo Controlled, Three Arm Clinical Study of Beverage Formulations (Formulation 2A and Formulation 2B) to Assess Improvement in Immunity and Management of General Health in Healthy Population - HBS 2 Dr. Denis Xavier, Dr. Pawan Kumar Godatwar, National institute of Ayurveda, Jaipur Coca-Cola India Pvt. Ltd. (Coca-Cola) 2019 Completed
67 An Interventional, Randomized, Parallel Group, Placebo Controlled, Three Arm Clinical Study of Beverage Formulations (Formulation 1A and Formulation 1B) to Assess Their Properties towards the Enhancement of Active Energy and Improving Immunity in Healthy Population - HBS 1 Dr. Denis Xavier, Dr. Pawan Kumar Godatwar, National institute of Ayurveda, Jaipur Coca-Cola India Pvt. Ltd. (Coca-Cola) 2019 Completed
68 An Interventional, Randomized, Parallel Group, Placebo Controlled, Three Arm Clinical Study of Beverage Formulations (Formulation 3A and Formulation 3B) to assess reduction in stress and improvement in immunity in Healthy Population – HBS 3 Dr. Denis Xavier, Dr. Pawan Kumar Godatwar, National institute of Ayurveda, Jaipur Coca-Cola India Pvt. Ltd. (Coca-Cola) 2019 Completed
69 STRIDE – Study of the effect of topical warm oxygen in treatment of diabetic foot ulcer Dr. Denis Xavier, Dr. Deepak Kamath Biotechnology Industry Research Assistance Council (BIRAC), Department of Science and Technology, Government of India 2019 Completed
70 RUMC - Rational use of Medicine Centres PI: Dr Denis Xavier; Co-I: Dr. Padmini Devi, Dr.Atiya Faruqui, Dr. Mangala Rao ICMR 2019 Completed
71 Breast Cancer in Pre-menopausal women- Evaluation of the role of steroid hormones in resistance to therapy Dr Jyothi S Prabhu Dept of Biotechnology- Wellcome-2019 2019 Completed
72 Evaluation of expression of Specified set of marker by Q-RT- PCR on tumor specimens belonging to the breast cancer cohort Dr Aruna Korlimarla Diagnostring Laboratories India Pvt Ltd 2018 Completed
73 Clinical and molecular landscapes of triple negative breast cancer in India and application to improved treatment decisions. Dr Aruna Korlimarla Institute of Cancer Research 2018 Completed
74 IMAGING NEEDLES: Deep tissue multi-modal molecular imaging needle-probes PI: Dr. Srirang Manohar, Co-I: Dr. Tony Raj DBT, NWO & ZonMw 2018 Completed
75 Effect of early stunting on body cell mass and fat mass in term appropriate for gestational age (AGA) infants. Department of Biotechnology 2018 Completed
76 Establish a reference standard for HIV Screening with the use of ELISA from finger stick blood sampled on DBS filter paper Dr. Savitha Nagaraj, Dr. Tony Raj Swasti Health Resource Center, Bangalore 2017 Completed
77 Evaluation of expression of chosen set of markers by immunohistochemistry on the tissue micro array (TMA) blocks of colorectal cancer (CRC) Dr Jyothi S Prabhu Sapiens Biosciences Pvt Ltd 2017 Completed
78 Demonstrating non-inferiority of a lower dose (500 mg) calcium supplementation during pregnancy for reducing preeclampsia (PE) and neonatal outcomes Harvard T.H. Chan School of Public Health / Bill & Melinda Gates Foundation 2017 Completed
79 IMPACT AF: Clustered Randomized Trial Protocol PI: Dr. Denis Xavier, Co-I: Dr. Deepak Kamath Duke Clinical Research Institute, USA 2017 Completed
80 G-CHF - A global registry on demographics, socio-economic and clinical factors, aetiologies, pathophysiology, management and outcomes of heart failure Dr. Kiron Varghese, Dr. Denis Xavier, Dr. Deepak Kamath Population Health Research Institute (PHRI), McMaster University 2017 Completed
81 How do the molecular landscapes of pre-menopausal triple-negative breast cancers differ between Indian and Western populations Dr. Aruna Korlimarla Newton fund, granted by Institute of Cancer Research, UK 2016 Completed
82 ENDORSE - Effect of behavioural interveNtion on medication aDherence amOng eldeRly with Select non-communicable disEases - Pilot Randomised Controlled Trial Dr. Jeffrey Pradeep Raj, Dr. Denis Xavier, Dr. Betsy Mathew Division of Clinical Research and Training 2016 Completed
83 Heart Rescue - An impact evaluation of the Heart Rescue India program: Assessing the effectiveness of a quality improvement program to improve access and care of acute cardiovascular disease PI: Dr. Denis Xavier, Co-I: Dr. Padmini Devi/ Dr. Ramakrishna Goud/ Dr. Twinkle Agrawal/ Dr. Farah Institute for Health Metrics and Evaluation, University of Washington, USA. 2016 Completed
84 Heart Rescue - An impact evaluation of the Heart Rescue India program: Assessing the effectiveness of a quality improvement program to improve access and care of acute cardiovascular disease PI: Dr. Denis Xavier, Co-I: Dr. Padmini Devi/ Dr. Ramakrishna Goud/ Dr. Twinkle Agrawal/ Dr. Farah Institute for Health Metrics and Evaluation, University of Washington, USA. 2016 Completed
85 PANACEA-HF (Piloting a quality improvement intervention for the optimal treatment of patients with chronic heart failure) PI: Dr. Deepak Kamath, Co-PI: Dr. Denis Xavier, Dr. Bhuvana K B India Alliance-DBT/ Wellcome Trust 2016 Completed
86 Validation of deep learning technology and algorithms in training systems for analysing medical diagnostic images Dr. Tony Raj, Dr. George D'Souza Intramural 2016 Completed
87 A qualitative analysis of nurses' attitudes towards patients with potentially stigmatized diagnosis Dr. Tony Raj, Dr. K Srinivasan, Dr. Maria Ekstrand Center for Emerging & Neglected Diseases (CEND) UC Berkeley, USA 2016 Completed
88 Fast tracking Bangalore's response to HIV through a pilot community-led testing model, the first in India Dr. Tony DS Raj, Dr. Savitha Nagraj Aidsfonds, Netherlands 2016 Completed
89 PROGRESS - Policy and peer mentor intervention proGrams on cardiovascular disease at work Sites in 3 South Asian countries Dr. Denis Xavier, Dr. Tony Raj, Dr. Dhinagaran Intramural 2015 Completed
90 Paediatric Nephrology Competence based Training Dr. Arpana Iyenger, Dr. Tony Raj Navajbai Ratan Tata Trust 2015 Completed
91 Kangaroo Mother Care (KMC) Adherence and Temperature Surveillance Project Dr. Prem Mony, Dr. Tony Raj Bill & Melinda Gates Foundation 2015 Completed
92 Reducing AIDS stigma among healthcare professionals in South India (in medical students) Dr. Tony Raj, Dr. K Srinivasan, Dr. Maria Ekstrand Center for Emerging & Neglected Diseases (CEND) UC Berkeley, USA 2015 Completed
93 Development of a database on REDCAP for data collection/surveys for a ‘Multicentre Study on Breast milk intake amongst Infants using Stable Isotope Technique’ Dr. Tinku Thomas, Dr. Tony Raj International Atomic Energy Agency (IAEA), Vienna, Austria 2015 Completed
94 Criticl care quality indicators analytics application Dr. Tony D.S. Raj Indian Society of Critical Care Medicine, Mumbai 2015 Completed
95 AUGUSTUS - Apixaban versus Vitamin K Antagonist in Atrial Fibrillation ACS / PCI Dr. Denis Xavier; Dr. Atiya Faruqui BMS / Pfizer 2015 Completed
96 Evaluation of anti cancer activity of CNX-013-B2 and other anti cancer agents in control of multiple cancer types Dr. T.S Sridhar Connexios life sciences pvt ltd 2015 Completed
97 Investigating the role of BLM helicaseas a global tumor suppressor: Clinical applications. Dr. Jyothi S. Prabhu Dept of Biotechnology 2015 Completed
98 Usage and Perception of medical related apps by healthcare professionals in a tertiary care teaching hospital in India Dr. Tony Raj, Dr. Abijeet V Waghmare Intramural 2014 Completed
99 Development of a text mining tool to mine biomedical text from discharge summaries Dr. Tony Raj, Dr. Sriram Sampath Intramural 2014 Completed
100 Laboratory based clinical validation of mDocTM wireless equipment in Healthy Indian Adults Dr. Tony Raj, Dr. Kedar Radhakrishna, Dr. Sejil Neurosynaptic Communications Pvt. Ltd. 2014 Completed
101 Mobile application to monitor quality of ICU care nationwide (CHITRA) Dr. Tony D S Raj, Dr. Sriram Sampath, Dr. Abijeet V Waghmare Indian Society of Critical Care Medicine 2014 Completed
102 Early detection of hypertension during pregnancy using increased frequency of blood pressure monitoring and information technology: A single group, prospective observational pilot study Dr. Abijeet Waghmare, Dr. Tony Raj Maternal Health Young Professionals (MHYP) India - Mentoring Program, Maternal Health Task Force, Boston, USA 2014 Completed
103 Developing A Novel Low-Cost RFID System for Increasing Hand Hygiene Compliance among Healthcare Workers in an ICU: Methodology Dr. Tony Raj, Dr. Sriram Sampath, Dr. Kedar Radhakrishna University of California at San Francisco, USA 2013 Completed
104 Reducing AIDS stigma among health professionals in India Dr. Maria Ekstrand, Dr. K Srinivasan, Dr. Tony Raj National Institutes of Health (NIH), USA 2013 Completed
105 Remote BioMonitoring (RBM) Project: Development of KMC sensor for position and temperature Dr. Prem K Mony 2013 Completed
106 DISC-B Denmark India in vivo screen for Cancer Biomarkers Dr. T.S Sridhar Dept of Biotechnology 2013 Completed
107 Preparation of Animations and Video clips for NAHRES e-learning modules Dr. Tony D.S. Raj IAEA 2013 Completed
108 Prospective Urban Rural Epidemiology (PURE) Study Dr. Prem K. Mony 2012 Ongoing
109 Examination of mechaniobiology of ER negative breast cancer tumors in Indian women Dr. T.S Sridhar Dept of Biotechnology 2012 Completed
110 Portal for medical algorithms Dr. Tony Raj St. John’s Research Society 2012 Completed
111 Rule-based computerized point of care decision support systems (SIgMA) Dr. Tony Raj, Dr. Kedar Radhakrishna, Dr. Abijeet V Waghmare, Dr. Ryan Fernandez St. John's Research Society 2012 Completed
112 Develop an interactive tool for the assessment of outcomes in hyperactive children and Schizophrenics Dr. Tony Raj Richmond Fellowship Society 2012 Completed
113 Develop Evidence based Medical Factsheets Dr. Tony Raj Intramural in collaboration with MedicInfo 2012 Completed
114 Designing and Developing a web-enabled reporting systems for histopathology Dr. Tony Raj Intramural 2012 Completed
115 Clinical Documentation and Decision Support Dr. Tony Raj Eclipsys Corporation 2011 Completed
116 Breast Cancer Patient support group activities Dr. T.S Sridhar Aadhara Project 2011 Completed
117 Assist in the finalization of a distance learning module on Helicobacter pylori infection Dr. Tony Raj Nutritional and Health – related Environmental Studies Section, International Atomic Energy Agency 2010 Completed
118 Predictive modeling systems for the Intensive care unit (ICU) Dr. Tony Raj Intramural 2010 Completed
119 Health Information Portability Dr. Tony Raj 2010 Completed
120 Breast Cancer Patient support group activities-2 Dr. T.S Sridhar Bagaria Education Trust 2009 Completed
121 Prospective longitudinal study of breast cancer Dr. T.S Sridhar Nadathur Holdings Pvt Ltd 2008 Completed
122 Growth Charts for Preterm Neonates Dr. Tony Raj Intramural 2008 Completed
123 Touch screen based Health Information Kiosk (iHealth Desk) Dr. Tony Raj Intramural 2007 Completed
124 Calculating Population Energy Requirements and Food Needs Dr. Tony Raj UN Food and Agriculture Organization (FAO) 2003 Completed

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